Chronic Endometritis – Understanding, Diagnosis, and Treatment

What Is Chronic Endometritis?

Chronic endometritis is a persistent inflammation of the uterine lining (endometrium) caused by infection or immune-related issues. It may not always cause noticeable symptoms but can silently affect fertility, implantation, and menstrual regularity. This condition often goes undetected in women facing repeated IVF failures or unexplained infertility. The inflammation disrupts the uterine environment, making it less receptive to embryo implantation.

Causes and Risk Factors

The main causes of chronic endometritis include bacterial infections, retained tissue after miscarriage, intrauterine devices (IUDs), or prolonged uterine infections. Sometimes, immune system imbalance or untreated pelvic inflammation also contributes to the condition. Women with recurrent miscarriages, painful periods, or abnormal uterine bleeding are at higher risk. Identifying these causes early can prevent long-term reproductive complications and improve fertility outcomes.

Common Signs and Symptoms

Many women with chronic endometritis experience mild or no symptoms, which makes diagnosis challenging. However, common signs include irregular periods, pelvic pain, abnormal discharge, or spotting between cycles. In fertility cases, chronic endometritis can cause repeated implantation failure or early pregnancy loss. Recognizing these symptoms and consulting a fertility specialist promptly is crucial for timely treatment.

Diagnosis of Chronic Endometritis

Accurate diagnosis is the first step toward effective treatment. At ISHA IVF & Fertility Center, doctors use advanced diagnostic tools such as endometrial biopsy, hysteroscopy, and microbial cultures to detect inflammation. Endometrial tissue analysis helps confirm the presence of plasma cells, the hallmark of chronic endometritis. Timely and precise diagnosis ensures targeted therapy and faster recovery.